Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | FNTA | P49354 | 1/20 | 0.56 |
| ▸ | FNTB | P49356 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | ERN1 | O75460 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305385 | 1.00 | MAPT (0.60) | MAPTPKMPOLBMEN1KMT2A | |
| SCHEMBL11191621 | 0.89 | MAPT (0.60) | MAPTPKMPOLBMEN1KMT2A | |
| SCHEMBL11191620 | 0.89 | MAPT (0.60) | MAPTPKMPOLBMEN1KMT2A | |
| SCHEMBL14011741 | 0.89 | MAPT (0.60) | MAPTPKMPOLBMEN1KMT2A | |
| SCHEMBL17413585 | 0.87 | ALDH1A1 (0.49) | MAPTPKMPOLBMEN1KMT2A | |
| SCHEMBL14011719 | 0.87 | MAPT (0.58) | MAPTPKMPOLBMEN1KMT2A | |
| SCHEMBL17395860 | 0.87 | MAPT (0.58) | MAPTPKMPOLBMEN1KMT2A | |
| SCHEMBL10182503 | 0.85 | MAPT (0.65) | MAPTPKMPOLBMEN1KMT2A | |
| SCHEMBL17395868 | 0.85 | MAPT (0.65) | MAPTPKMPOLBMEN1KMT2A | |
| SCHEMBL17395890 | 0.83 | MAPT (0.66) | MAPTPKMPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107250142-B | Group 8 transition metal catalyst, method for producing same and use thereof in metathesis reactions | 光明创新（武汉）有限公司 | 2020-10-30 | — | — | CN | disclosed |
| US-10160828-B2 | Group 8 transition metal catalysts and method for making same and process for use of same in metathesis reaction | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2018-12-25 | — | — | US | disclosed |
| US-20170145152-A1 | GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN METATHESIS REACTION | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2017-05-25 | — | — | US | disclosed |
| EP-3164409-A1 | GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN METATHESIS REACTION | Guang Ming Innovation Company (Wuhan) (CN) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016000242-A1 | GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN METATHESIS REACTION | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2016-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145152-A1 | GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN METATHESIS REACTION | F8, COASY, FADS1 | MAPT 3667/4885PKM 332/4885POLB 3132/4885 |
| US-10160828-B2 | Group 8 transition metal catalysts and method for making same and process for use of same in metathesis reaction | F8, COASY, FADS1 | MAPT 3667/4885PKM 332/4885POLB 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.