Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 2/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 4/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | KDM5A | P29375 | 3/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ADA | P00813 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20497264 | 0.91 | KDM2B (0.52) | CPB1KDM2BPIM1PIM2PIM3 | |
| SCHEMBL30364250 | 0.89 | KDM5A (0.43) | CPB1KDM2BKDM5ACPB2ADA | |
| SCHEMBL13406413 | 0.86 | KDM2B (0.49) | CPB1KDM2BPIM1PIM2KDM5A | |
| SCHEMBL6504137 | 0.85 | CPB2 (0.47) | CPB1KDM5ACPB2MEN1KMT2A | |
| SCHEMBL20497250 | 0.82 | PIM1 (0.45) | KDM2BPIM1PIM2PIM3PARP1 | |
| SCHEMBL20497248 | 0.82 | PIM1 (0.45) | KDM2BPIM1PIM2PIM3PARP1 | |
| SCHEMBL13406325 | 0.81 | PLAT (0.45) | CPB1KDM2BKDM5ACPB2MEN1 | |
| SCHEMBL19589410 | 0.79 | KDM2B (0.49) | CPB1KDM2BKDM5AALDH1A1KMT2A | |
| SCHEMBL2821284 | 0.75 | CPB1 (0.46) | CPB1KDM2BPIM1MEN1ALDH1A1 | |
| SCHEMBL20497261 | 0.75 | KDM2B (0.44) | KDM2BPIM1PIM2PIM3PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164509-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | Celgene Quanticel Research, Inc. (US) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016004105-A1 | INHIBITORS OF LYSINE SPECIFIC DEMETHYLASE-1 | Quanticel Pharmaceuticals, Inc. (US) | 2016-01-07 | — | — | WO | disclosed |