Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ABHD10 | Q9NUJ1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | EIF4A1 | P60842 | 15/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180245 | 0.78 | CYP3A4 (0.45) | CYP3A4ALDH1A1TSHRCYP2C19ABHD10 | |
| SCHEMBL20006140 | 0.78 | CYP3A4 (0.49) | CYP3A4ALDH1A1TSHRCYP2C19ABHD10 | |
| SCHEMBL20006458 | 0.74 | CYP3A4 (0.46) | CYP3A4ALDH1A1TSHRCYP2C19ABHD10 | |
| SCHEMBL20006092 | 0.74 | EIF4A1 (0.51) | CYP3A4ALDH1A1TSHRCYP2C19ABHD10 | |
| SCHEMBL20006494 | 0.73 | ABHD10 (0.57) | CYP3A4ABHD10EIF4A1NFKB1RELA | |
| SCHEMBL20006501 | 0.73 | CYP3A4 (0.47) | CYP3A4ALDH1A1TSHRCYP2C19ABHD10 | |
| SCHEMBL29532250 | 0.72 | ABHD10 (0.71) | CYP3A4ABHD10EIF4A1NFKB1RELA | |
| SCHEMBL17414107 | 0.72 | ABHD10 (0.71) | CYP3A4ABHD10EIF4A1NFKB1RELA | |
| SCHEMBL18836092 | 0.72 | ABHD10 (0.71) | CYP3A4ABHD10EIF4A1NFKB1RELA | |
| SCHEMBL20006331 | 0.71 | CYP3A4 (0.41) | CYP3A4ALDH1A1TSHRCYP2C19ABHD10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164393-A1 | FLAVAGLINE DERIVATIVES | Pierre Fabre Médicament (FR) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016001441-A1 | FLAVAGLINE DERIVATIVES | PIERRE FABRE MEDICAMENT (FR) | 2016-01-07 | — | — | WO | disclosed |