Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397148 | 1.00 | PIK3CD (0.40) | PIK3CDPIK3CBPIK3CAPIK3CGSLC11A2 | |
| SCHEMBL18989207 | 0.84 | PIK3CD (0.30) | PIK3CDPIK3CB | |
| SCHEMBL18988992 | 0.79 | PIK3CD (0.42) | PIK3CDPIK3CBPIK3CASLC11A2 | |
| SCHEMBL17397091 | 0.77 | PIK3CD (0.37) | PIK3CDPIK3CBPIK3CASLC11A2 | |
| SCHEMBL17397174 | 0.77 | PIK3CD (0.42) | PIK3CDPIK3CBPIK3CAPIK3CGSLC11A2 | |
| SCHEMBL17397173 | 0.77 | PIK3CD (0.41) | PIK3CDPIK3CBPIK3CAPIK3CGSLC11A2 | |
| SCHEMBL17397246 | 0.77 | PIK3CD (0.53) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL17397243 | 0.77 | PIK3CD (0.53) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL18989021 | 0.77 | PIK3CD (0.53) | PIK3CDPIK3CBPIK3CAPIK3CG | |
| SCHEMBL17397145 | 0.77 | PIK3CD (0.53) | PIK3CDPIK3CBPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |
| EP-3164400-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | Lupin Limited (IN) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016001855-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2016-01-07 | — | — | WO | disclosed |