Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397173 | 0.84 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBMAPTALDH1A1 | |
| SCHEMBL17397174 | 0.82 | PIK3CD (0.42) | PIK3CDPIK3CAPIK3CBSLC11A2 | |
| SCHEMBL18989286 | 0.80 | PIK3CD (0.40) | PIK3CDPIK3CAPIK3CBTP53 | |
| SCHEMBL19006238 | 0.79 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBSLC11A2 | |
| SCHEMBL17397146 | 0.79 | PIK3CD (0.40) | PIK3CDPIK3CAPIK3CBSLC11A2 | |
| SCHEMBL17397148 | 0.79 | PIK3CD (0.40) | PIK3CDPIK3CAPIK3CBSLC11A2 | |
| SCHEMBL19006144 | 0.77 | PIK3CD (0.39) | PIK3CDPIK3CAPIK3CB | |
| SCHEMBL18989239 | 0.76 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBTP53MAPT | |
| SCHEMBL18989139 | 0.76 | PIK3CD (0.40) | PIK3CDPIK3CAPIK3CBTP53MAPT | |
| SCHEMBL17397153 | 0.75 | PIK3CD (0.68) | PIK3CDPIK3CAPIK3CBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |