Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28593515 | 0.82 | MEN1 (0.40) | TAAR1MAOB | |
| SCHEMBL4764220 | 0.81 | MAPT (0.41) | MAOBSMN1; SMN2TDP1 | |
| SCHEMBL694287 | 0.81 | MAOB (0.48) | MAOB | |
| Hydrochloric Acid SCHEMBL8207718 | 0.74 | EED (0.46) | TAAR1MAOBIDO1AGXTSMN1; SMN2 | |
| SCHEMBL29889395 | 0.74 | EED (0.52) | TAAR1IDO1AGXTEED | |
| SCHEMBL26187550 | 0.74 | EED (0.52) | TAAR1IDO1AGXTEED | |
| SCHEMBL29890848 | 0.74 | EED (0.52) | TAAR1IDO1AGXTEED | |
| Hydrochloric Acid SCHEMBL30648851 | 0.73 | EED (0.51) | TAAR1MAOBIDO1AGXTEED | |
| SCHEMBL26187523 | 0.73 | TAAR1 (0.44) | TAAR1MAOBIDO1AGXTSMN1; SMN2 | |
| SCHEMBL27532142 | 0.72 | MAPT (0.37) | MAOBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016000615-A1 | HETEROARYL COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-01-07 | — | — | WO | disclosed |