Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26187550 | 1.00 | EED (0.52) | EEDGBA1SLC6A4EP300CHRM2 | |
| SCHEMBL29889395 | 1.00 | EED (0.52) | EEDGBA1SLC6A4EP300CHRM2 | |
| Hydrochloric Acid SCHEMBL30648851 | 0.98 | EED (0.51) | EEDGBA1SLC6A4EP300CHRM2 | |
| Hydrochloric Acid SCHEMBL2634704 | 0.89 | GBA1 (0.61) | EEDGBA1SLC6A4EP300TAAR1 | |
| Hydrochloric Acid SCHEMBL8207718 | 0.87 | EED (0.46) | EEDGBA1SLC6A4TAAR1IDO1 | |
| SCHEMBL26187523 | 0.86 | TAAR1 (0.44) | EEDGBA1SLC6A4TAAR1IDO1 | |
| Hydrochloric Acid SCHEMBL8208491 | 0.83 | EED (0.49) | EEDGBA1SLC6A4TAAR1IDO1 | |
| SCHEMBL5618486 | 0.82 | TAAR1 (0.42) | EEDGBA1SLC6A4EP300CHRM2 | |
| SCHEMBL24187547 | 0.81 | TAAR1 (0.48) | GBA1TAAR1IDO1AGXT | |
| SCHEMBL30431712 | 0.81 | TAAR1 (0.48) | GBA1TAAR1IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12336991-B2 | Factor XIIA inhibitors | UNIVERSITY OF LEEDS (GB) | 2025-06-24 | — | — | US | disclosed |
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | UNIVERSITY OF LEEDS (GB) | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220305011-A1 | FACTOR XIIA INHIBITORS | F11, F13B, F12 | EED 3279/4885GBA1 536/4885SLC6A4 4480/4885 |
| US-12336991-B2 | Factor XIIA inhibitors | F11, F13B, F12 | EED 3279/4885GBA1 536/4885SLC6A4 4480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.