Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397505 | 0.88 | CTSK (0.55) | TSHRCTSKCTSSCACNA1B | |
| SCHEMBL15238943 | 0.88 | TSHR (0.47) | TSHRCTSKCTSSMEN1KMT2A | |
| SCHEMBL15238831 | 0.88 | TSHR (0.47) | TSHRCTSKCTSSMEN1KMT2A | |
| SCHEMBL28820410 | 0.88 | TSHR (0.47) | TSHRCTSKCTSSMEN1KMT2A | |
| SCHEMBL6121963 | 0.87 | CTSK (0.46) | TSHRCTSKCTSSMEN1KMT2A | |
| SCHEMBL6121854 | 0.87 | CTSK (0.46) | TSHRCTSKCTSSMEN1KMT2A | |
| SCHEMBL17009266 | 0.87 | CTSK (0.48) | CTSKCTSS | |
| SCHEMBL16762045 | 0.86 | CTSK (0.46) | TSHRCTSKCTSSMEN1KMT2A | |
| SCHEMBL16762228 | 0.86 | CTSK (0.46) | TSHRCTSKCTSSMEN1KMT2A | |
| SCHEMBL17009335 | 0.85 | PPARG (0.43) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3164127-A1 | COMPOSITIONS AND METHODS TO IMPROVE ADOPTIVE CELL THERAPIES | 7 HILLS INTERESTS, LLC (US) | 2017-05-10 | — | — | EP | disclosed |
| WO-2016003980-A1 | COMPOSITIONS AND METHODS TO IMPROVE ADOPTIVE CELL THERAPIES | 7 HILLS INTERESTS LLC (US) | 2016-01-07 | — | — | WO | disclosed |