Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17397520 | 0.87 | TSHR (0.44) | CTSKCTSS | |
| SCHEMBL17009335 | 0.86 | PPARG (0.43) | CTSKCTSSPPARAPPARGALDH1A1 | |
| SCHEMBL28820353 | 0.85 | CTSK (0.49) | CTSKCTSSALDH1A1SMN1; SMN2CTSL | |
| SCHEMBL15239051 | 0.85 | CTSK (0.49) | CTSKCTSSALDH1A1SMN1; SMN2CTSL | |
| SCHEMBL6123057 | 0.83 | CTSK (0.53) | CTSKCTSSPPARAPPARGALDH1A1 | |
| SCHEMBL28820406 | 0.83 | CTSK (0.52) | CTSKCTSSALDH1A1SMN1; SMN2 | |
| SCHEMBL15238716 | 0.83 | CTSK (0.52) | CTSKCTSSALDH1A1SMN1; SMN2 | |
| SCHEMBL15238958 | 0.83 | CTSK (0.52) | CTSKCTSSALDH1A1SMN1; SMN2 | |
| SCHEMBL15238991 | 0.83 | CTSK (0.52) | CTSKCTSSALDH1A1SMN1; SMN2 | |
| SCHEMBL18190216 | 0.83 | ALDH1A1 (0.46) | CTSKALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288585-A2 | NOVEL COMPOSITIONS AND METHODS FOR IMMUNOTHERAPIES COMPRISING SMALL MOLECULE INTEGRIN RECEPTOR-LIGAND AGONIST ADJUVANTS | 7 HILLS INTERESTS, LLC (US) | 2018-03-07 | — | — | EP | disclosed |
| EP-3104867-A1 | COMPOSITIONS AND METHODS TO IMPROVE THE HOMING AND GRAFTING OF HEMATOPOETIC STEM CELLS | 7 HILLS INTERESTS, LLC (US) | 2016-12-21 | — | — | EP | disclosed |
| WO-2016176400-A2 | NOVEL COMPOSITIONS AND METHODS FOR IMMUNOTHERAPIES COMPRISING SMALL MOLECULE INTEGRIN RECEPTOR-LIGAND AGONIST ADJUVANTS | 7 HILLS INTERESTS LLC (US) | 2016-11-03 | — | — | WO | disclosed |
| WO-2015123447-A1 | COMPOSITIONS AND METHODS TO IMPROVE THE HOMING AND GRAFTING OF HEMATOPOETIC STEM CELLS | 7 HILLS PHARMA, LLC (US) | 2015-08-20 | — | — | WO | disclosed |