Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 3/20 | 0.75 |
| ▸ | CA1 | P00915 | 1/20 | 0.75 |
| ▸ | CA2 | P00918 | 1/20 | 0.75 |
| ▸ | CA9 | Q16790 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 8/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.74 |
| ▸ | RECQL | P46063 | 2/20 | 0.74 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.74 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | ESR1 | P03372 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | PGR | P06401 | 3/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18658846 | 0.89 | LMNA (0.76) | STSCA1CA2CA9LMNA | |
| SCHEMBL27369500 | 0.89 | LMNA (0.76) | STSCA1CA2CA9LMNA | |
| SCHEMBL14951243 | 0.89 | LMNA (0.76) | STSCA1CA2CA9LMNA | |
| SCHEMBL7530939 | 0.89 | LMNA (0.76) | STSCA1CA2CA9LMNA | |
| SCHEMBL14305721 | 0.89 | LMNA (0.76) | STSCA1CA2CA9LMNA | |
| SCHEMBL13596253 | 0.89 | LMNA (0.76) | STSCA1CA2CA9LMNA | |
| SCHEMBL26073723 | 0.88 | LMNA (0.74) | STSCA1CA2CA9LMNA | |
| SCHEMBL22675144 | 0.87 | KMT2A (0.76) | STSCA1CA2CA9LMNA | |
| SCHEMBL7538281 | 0.87 | KMT2A (0.76) | STSCA1CA2CA9LMNA | |
| SCHEMBL9273487 | 0.87 | LMNA (0.82) | STSCA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9226912-B2 | Acetyltanshinone IIA (ATA) as anticancer agent | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-01-05 | — | — | US | disclosed |