Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21620295 | 0.87 | KCNJ11 (0.49) | ALDH1A1RAB9ANPC1KCNJ11MAPT | |
| SCHEMBL9894627 | 0.86 | PTGS1 (0.51) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL18724342 | 0.85 | MEN1 (0.44) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL12931919 | 0.83 | MEN1 (0.41) | CYP1A2RAB9ANPC1KCNJ11MAPT | |
| SCHEMBL1275465 | 0.82 | MEN1 (0.48) | ALDH1A1RAB9ANPC1MAPTMEN1 | |
| SCHEMBL1274348 | 0.81 | KCNJ11 (0.42) | CYP1A2RAB9ANPC1KCNJ11MAPT | |
| SCHEMBL1275827 | 0.81 | JAK2 (0.43) | ALDH1A1RAB9ANPC1KCNJ11MAPT | |
| SCHEMBL299472 | 0.80 | LMNA (0.47) | ALDH1A1RAB9ANPC1KCNJ11MEN1 | |
| SCHEMBL9894400 | 0.78 | S1PR3 (0.47) | KCNJ11 | |
| SCHEMBL3023983 | 0.78 | MAPT (0.41) | RAB9ANPC1KCNJ11MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227923-B2 | Pesticidal carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-05 | — | — | US | disclosed |