Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | BLM | P54132 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12763980 | 0.93 | KMT2A (0.37) | KMT2AMEN1GAABLMPOLB | |
| SCHEMBL14078008 | 0.92 | — | — | |
| SCHEMBL12836879 | 0.90 | KMT2A (0.32) | KMT2AMEN1GAABLMPOLB | |
| SCHEMBL12763960 | 0.85 | ALDH1A1 (0.32) | KMT2AMEN1GAABLMPOLB | |
| SCHEMBL12836878 | 0.74 | ABCB1 (0.35) | KMT2AMEN1GAABLMPOLB | |
| SCHEMBL14078007 | 0.73 | MEN1 (0.32) | KMT2AMEN1GAABLMPOLB | |
| SCHEMBL14078005 | 0.73 | — | — | |
| SCHEMBL26428065 | 0.72 | KDM4E (0.34) | KMT2AMEN1BLMUSP2CASP7 | |
| SCHEMBL22247631 | 0.72 | FTO (0.33) | KMT2AMEN1BLMUSP2CASP7 | |
| SCHEMBL25208865 | 0.71 | KDM4E (0.34) | KMT2AMEN1BLMPOLBUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9228225-B2 | Xanthene dyes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2016-01-05 | — | — | US | disclosed |