Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 9/20 | 0.64 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.64 |
| ▸ | PPARG | P37231 | 11/20 | 0.49 |
| ▸ | PPARA | Q07869 | 11/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17399629 | 0.88 | OSBP (0.64) | OSBPOSBP2PPARGPPARA | |
| Schweinfurthin B SCHEMBL12042782 | 0.87 | OSBP (0.85) | OSBPOSBP2PPARGPPARA | |
| Schweinfurthin B SCHEMBL847454 | 0.87 | OSBP (0.85) | OSBPOSBP2PPARGPPARA | |
| 3-Deoxyschweinfurthin B SCHEMBL10043035 | 0.82 | OSBP (0.86) | OSBPOSBP2PPARGPPARA | |
| Schweinfurthin E SCHEMBL24867154 | 0.79 | OSBP (0.77) | OSBPOSBP2 | |
| Schweinfurthin A SCHEMBL847068 | 0.78 | OSBP (1.00) | OSBPOSBP2PPARGPPARA | |
| Schweinfurthin A SCHEMBL29378071 | 0.78 | OSBP (1.00) | OSBPOSBP2PPARGPPARA | |
| Schweinfurthin A SCHEMBL20003740 | 0.78 | OSBP (1.00) | OSBPOSBP2PPARGPPARA | |
| SCHEMBL2073634 | 0.77 | OSBP (0.80) | OSBPOSBP2PPARGPPARA | |
| SCHEMBL2073637 | 0.77 | OSBP (0.80) | OSBPOSBP2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732915-B1 | SCHWEINFURTHIN ANALOGUES | UNIV IOWA RES FOUND (US) | 2016-01-06 | — | — | EP | disclosed |