SCHEMBL1740016

SCHEMBL1740016

[CH2]CCSc1ccc(C)cc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
ALDH1A1 P00352 5/20 0.48
MAPT P10636 2/20 0.48
HPGD P15428 8/20 0.44
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MAPK1 P28482 1/20 0.42
DRD2 P14416 1/20 0.41
DRD4 P21917 1/20 0.41
POLB P06746 1/20 0.41
TSHR P16473 1/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
ALOX12 P18054 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7595139 0.86 NPC1 (0.48) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL5168911 0.85 NPC1 (0.65) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL9808095 0.80 NPC1 (0.55) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL1199703 0.80 NPC1 (0.45) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL5172043 0.80 POLB (0.56) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL28435021 0.78 POLB (0.54) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL8362962 0.78 NPC1 (0.53) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL5169781 0.78 POLB (0.54) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL9770471 0.76 TDP1 (0.53) NPC1RAB9AALDH1A1MAPTHPGD
SCHEMBL5171094 0.76 ALDH1A1 (0.71) NPC1RAB9AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8669025-B2 Polymerizable composition, cured film, color filter, method of producing color filter and solid-state image sensor FUJIFILM CORPORATION (JP) 2014-03-11 US disclosed
EP-2390272-A1 Polymerizable composition, cured film, color filter, method of producing color filter and solid-state image sensor FUJIFILM Corporation (JP) 2011-11-30 EP disclosed
US-20110255570-A1 ADAPTIVE FREQUENCY HOPPING IN TIME-SLOTTED BASED WIRELESS NETWORK HITACHI, LTD. (JP) 2011-10-20 US disclosed
EP-0706523-B1 SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES BYK GULDEN LOMBERG CHEM FAB (DE) 2001-01-24 EP disclosed
US-5859030-A Substituted arylalkylthioalkylthiopyridines for use in the control of helicobacter bacteria BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1999-01-12 US disclosed
US-5773451-A BACTERICIDES FOR HELICOBACTER BACTERIA BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1998-06-30 US disclosed
EP-0764161-A1 SUBSTITUTED ARYLALKYLTHIOALKYLTHIOPYRIDINES FOR USE IN THE CONTROL OF HELICOBACTER BACTERIA Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1997-03-26 EP disclosed
EP-0706523-A1 SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1996-04-17 EP disclosed
WO-1996000224-A1 4-S- AND N-SUBSTITUTED 6-ALKYLPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1996-01-04 WO disclosed
WO-1995034554-A1 SUBSTITUTED ARYLALKYLTHIOALKYLTHIOPYRIDINES FOR USE IN THE CONTROL OF HELICOBACTER BACTERIA BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1995-12-21 WO disclosed
WO-1995001351-A1 SUBSTITUTED ARYLTHIOALKYLTHIOPYRIDINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1995-01-12 WO disclosed