SCHEMBL1740131

SCHEMBL1740131

CCn1c2ccccc2c2cc([C]=O)ccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.59
KDM4E B2RXH2 6/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
ALDH1A1 P00352 2/20 0.59
MAPK1 P28482 2/20 0.59
HTT P42858 2/20 0.59
HPGD P15428 1/20 0.59
HBB P68871 1/20 0.59
HSD17B10 Q99714 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
LMNA P02545 5/20 0.56
POLB P06746 2/20 0.54
NPSR1 Q6W5P4 1/20 0.54
RORC P51449 7/20 0.53
PKM P14618 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
NPY5R Q15761 1/20 0.49
PTGER4 P35408 1/20 0.49
SRC P12931 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29643208 0.84 PTGER4 (0.63) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL5892136 0.84 PTGER4 (0.63) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL1052731 0.84 MAPT (0.59) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL9650799 0.79 ALDH1A1 (0.66) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL13979310 0.79 KDM4E (0.70) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL151563 0.78 ALDH1A1 (0.75) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL29963695 0.78 ALDH1A1 (0.75) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL29360167 0.78 ALDH1A1 (0.75) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL31027168 0.78 MAPT (0.69) MAPTKDM4EMEN1KMT2AALDH1A1
SCHEMBL14805532 0.78 MAPT (0.69) MAPTKDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8669025-B2 Polymerizable composition, cured film, color filter, method of producing color filter and solid-state image sensor FUJIFILM CORPORATION (JP) 2014-03-11 US disclosed
EP-2390272-A1 Polymerizable composition, cured film, color filter, method of producing color filter and solid-state image sensor FUJIFILM Corporation (JP) 2011-11-30 EP disclosed
US-20110255570-A1 ADAPTIVE FREQUENCY HOPPING IN TIME-SLOTTED BASED WIRELESS NETWORK HITACHI, LTD. (JP) 2011-10-20 US disclosed
US-6388081-B1 4-substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries LION BIOSCIENCE AG (DE) 2002-05-14 US disclosed
US-6262269-B1 4-Substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries TREGA BIOSCIENCES, INC. 2001-07-17 US disclosed