Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.63 |
| ▸ | RORC | P51449 | 9/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HBB | P68871 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5892136 | 1.00 | PTGER4 (0.63) | PTGER4RORCKDM4EMAPTALDH1A1 | |
| SCHEMBL21076080 | 0.92 | RORC (0.52) | PTGER4RORCKDM4EMAPTALDH1A1 | |
| SCHEMBL21599721 | 0.90 | PTGER4 (0.59) | PTGER4RORCKDM4EMAPTALDH1A1 | |
| SCHEMBL16119985 | 0.88 | ALDH1A1 (0.56) | PTGER4RORCKDM4EMAPTALDH1A1 | |
| SCHEMBL97588 | 0.85 | PTGER4 (0.54) | PTGER4RORC | |
| SCHEMBL17614522 | 0.85 | PTGER4 (0.53) | PTGER4RORCKDM4EMAPTALDH1A1 | |
| SCHEMBL18010701 | 0.84 | PTGER4 (0.52) | PTGER4RORCKDM4EMAPTALDH1A1 | |
| SCHEMBL18010711 | 0.84 | PTGER4 (0.52) | PTGER4RORCKDM4EMAPTALDH1A1 | |
| SCHEMBL1052731 | 0.84 | MAPT (0.59) | PTGER4RORCKDM4EMAPTALDH1A1 | |
| SCHEMBL1740131 | 0.84 | MAPT (0.59) | PTGER4RORCKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109206360-B | Carbazole amide derivative or salt thereof, and preparation method and application thereof | 复旦大学 | 2022-05-17 | — | — | CN | disclosed |