Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17401396 | 0.90 | ENPP2 (0.67) | ENPP2 | |
| SCHEMBL17401439 | 0.90 | ENPP2 (0.67) | ENPP2 | |
| SCHEMBL17401489 | 0.88 | ENPP2 (0.60) | ENPP2 | |
| SCHEMBL17401460 | 0.88 | ENPP2 (0.65) | ENPP2 | |
| SCHEMBL17401488 | 0.87 | ENPP2 (0.61) | ENPP2 | |
| SCHEMBL17401462 | 0.87 | ENPP2 (0.61) | ENPP2 | |
| SCHEMBL17401467 | 0.87 | ENPP2 (0.64) | ENPP2 | |
| SCHEMBL17401477 | 0.87 | ENPP2 (0.64) | ENPP2 | |
| SCHEMBL17401495 | 0.86 | ENPP2 (0.62) | ENPP2 | |
| SCHEMBL17401433 | 0.86 | ENPP2 (0.62) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160002247-A1 | 8-SUBSTITUTED IMIDAZOPYRIMIDINONE DERIVATIVE HAVING AUTOTAXIN INHIBITORY ACTIVITY | THE UNIVERSITY OF TOKYO (JP) | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002247-A1 | 8-SUBSTITUTED IMIDAZOPYRIMIDINONE DERIVATIVE HAVING AUTOTAXIN INHIBITORY ACTIVITY | ENPP2, UACA, IAPP | ENPP2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.