SCHEMBL1740295

SCHEMBL1740295

C=Cc1ccccc1C(=C)C(=O)OC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
LMNA P02545 3/20 0.38
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 2/20 0.37
CFTR P13569 1/20 0.37
POLB P06746 2/20 0.36
KDM4E B2RXH2 2/20 0.36
ATM Q13315 1/20 0.36
CYP3A4 P08684 1/20 0.36
NFE2L2 Q16236 2/20 0.36
MEN1 O00255 1/20 0.36
PLIN1 O60240 1/20 0.36
PLIN5 Q00G26 1/20 0.36
KMT2A Q03164 1/20 0.36
ABHD5 Q8WTS1 1/20 0.36
AR P10275 1/20 0.35
MAOB P27338 1/20 0.35
BACE1 P56817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26695691 0.86 LMNA (0.40) MAPTNPSR1LMNATSHRALDH1A1
SCHEMBL3807002 0.82 MEN1 (0.34) MAPTLMNATSHRALDH1A1HSD17B10
SCHEMBL28094665 0.81 ALDH1A1 (0.46) LMNATSHRALDH1A1HSD17B10KDM4E
SCHEMBL29067563 0.81 ALDH1A1 (0.46) MAPTLMNATSHRALDH1A1HSD17B10
SCHEMBL61520 0.80 TSHR (0.55) MAPTLMNATSHRALDH1A1HSD17B10
SCHEMBL11232755 0.79 ALDH1A1 (0.56) MAPTNPSR1LMNATSHRALDH1A1
SCHEMBL30075844 0.79 ALDH1A1 (0.56) MAPTNPSR1LMNATSHRALDH1A1
SCHEMBL1483930 0.79 ALDH1A1 (0.56) MAPTNPSR1LMNATSHRALDH1A1
SCHEMBL25141448 0.78 ALDH1A1 (0.39) LMNATSHRALDH1A1HSD17B10CFTR
SCHEMBL9027781 0.78 CA1 (0.39) MAPTLMNATSHRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2389395-A1 RAFT POLYMERISATION Commonwealth Scientific and Industrial Research Organisation (AU) 2011-11-30 EP disclosed
US-20110256644-A1 MASKS FOR MICROLITHOGRAPHY AND METHODS OF MAKING AND USING SUCH MASKS MICRON TECHNOLOGY, INC. (US) 2011-10-20 US disclosed
WO-2010083569-A1 RAFT POLYMERISATION COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2010-07-29 WO disclosed