SCHEMBL1740441

SCHEMBL1740441

Nc1ccc(C(c2ccc(N)cc2)C(c2ccc(N3C(=O)C=CC3=O)cc2)c2ccc(N3C(=O)C=CC3=O)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 15/20 0.63
FAAH O00519 5/20 0.58
HSP90AA1 P07900 4/20 0.48
PKM P14618 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
MAPK1 P28482 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
ALDH1A1 P00352 2/20 0.44
LMNA P02545 2/20 0.44
CCR6 P51684 2/20 0.44
MEN1 O00255 1/20 0.44
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44
DDAH1 O94760 1/20 0.44
BCHE P06276 1/20 0.44
CACNA1B Q00975 1/20 0.43
APBA1 Q02410 1/20 0.43
APOBEC3G Q9HC16 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8564255 0.90 MGLL (0.71) MGLLFAAHHSP90AA1PKMTDP1
SCHEMBL3665731 0.78 MGLL (0.65) MGLLFAAHHSP90AA1PKMTDP1
SCHEMBL3482327 0.78 MGLL (1.00) MGLLFAAHHSP90AA1PKMTDP1
SCHEMBL22862128 0.77 MGLL (0.71) MGLLFAAHHSP90AA1PKMTDP1
4,4'-Methylenedianiline SCHEMBL7738791 0.77 MGLL (0.81) MGLLFAAHHSP90AA1PKMTDP1
SCHEMBL19844745 0.77 MGLL (0.81) MGLLFAAHHSP90AA1PKMTDP1
SCHEMBL95324 0.76 MGLL (1.00) MGLLFAAHHSP90AA1PKMTDP1
SCHEMBL22975399 0.74 MGLL (0.65) MGLLFAAHHSP90AA1PKMTDP1
Aniline SCHEMBL29273152 0.74 MGLL (0.78) MGLLFAAHHSP90AA1PKMTDP1
SCHEMBL2363989 0.74 MGLL (0.77) MGLLFAAHHSP90AA1PKMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3380535-B1 THERMALLY REVERSIBLE POLYMER CROSSLINKING FOR PRESSURE SENSITIVE ADHESIVES ROHM & HAAS (US) 2020-09-16 EP disclosed
EP-3380535-A1 THERMALLY REVERSIBLE POLYMER CROSSLINKING FOR PRESSURE SENSITIVE ADHESIVES Rohm and Haas Company (US) 2018-10-03 EP disclosed
WO-2017091284-A1 THERMALLY REVERSIBLE POLYMER CROSSLINKING FOR PRESSURE SENSITIVE ADHESIVES ROHM AND HAAS COMPANY (US) 2017-06-01 WO disclosed
EP-2389406-A1 HOMOGENEOUS BISMALEIMIDE - TRIAZINE - EPOXY COMPOSITIONS USEFUL FOR THE MANUFACTURE OF ELECTRICAL LAMINATES Dow Global Technologies LLC (US) 2011-11-30 EP disclosed
WO-2010075006-A1 HOMOGENEOUS BISMALEIMIDE - TRIAZINE - EPOXY COMPOSITIONS USEFUL FOR THE MANUFACTURE OF ELECTRICAL LAMINATES DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-01 WO disclosed
WO-1998030374-A1 PROCESS FOR PREPARING PREFORMS AND MOLDED ARTICLES THE DOW CHEMICAL COMPANY (US) 1998-07-16 WO disclosed