SCHEMBL3482327

SCHEMBL3482327

CC(C)c1ccc(N2C(=O)C=CC2=O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 14/20 1.00
FAAH O00519 5/20 0.65
L3MBTL1 Q9Y468 1/20 0.55
HSP90AA1 P07900 2/20 0.54
PKM P14618 2/20 0.54
MAPK1 P28482 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
HPGD P15428 1/20 0.48
HTT P42858 1/20 0.48
CCR6 P51684 1/20 0.48
ATM Q13315 1/20 0.48
DDAH1 O94760 1/20 0.48
BCHE P06276 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22862058 0.94 MGLL (0.89) MGLLFAAHL3MBTL1HSP90AA1PKM
SCHEMBL9156707 0.89 MGLL (0.79) MGLLFAAHL3MBTL1HSP90AA1PKM
SCHEMBL2363989 0.87 MGLL (0.77) MGLLFAAHHSP90AA1PKMMAPK1
SCHEMBL23599861 0.83 MGLL (0.71) MGLLFAAHHSP90AA1PKMMAPK1
SCHEMBL27558830 0.83 MGLL (0.71) MGLLFAAHHSP90AA1PKMMAPK1
SCHEMBL19156143 0.83 MGLL (0.71) MGLLFAAHHSP90AA1PKMMAPK1
SCHEMBL1255913 0.82 MGLL (0.71) MGLLFAAHHSP90AA1PKMMAPK1
SCHEMBL22862128 0.82 MGLL (0.71) MGLLFAAHHSP90AA1PKMMAPK1
SCHEMBL8564255 0.82 MGLL (0.71) MGLLFAAHHSP90AA1PKMMAPK1
SCHEMBL95324 0.81 MGLL (1.00) MGLLFAAHHSP90AA1PKMMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110724154-A Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof 湖北科技学院 2020-01-24 CN claimed
US-20250092171-A1 HIGH-PURITY 4-(2-BROMOETHYL)BENZENESULFONIC ACID, HIGH-PURITY STYRENESULFONIC ACID COMPOUND DERIVED THEREFROM, AND POLYMER THEREOF, AND METHODS FOR PRODUCING SAME TOSOH FINECHEM CORPORATION (JP) 2025-03-20 US disclosed
EP-3666753-B1 HIGH-PURITY AMPHIPATHIC ARYLSULFONIC ACID AMINE SALT VINYL MONOMER AND COPOLYMER THEREOF TOSOH FINECHEM CORP (JP) 2024-09-11 EP disclosed
US-20240191087-A1 WATER DISPERSIBLE SULFONATED THERMOPLASTIC COPOLYMER FOR USE IN ADDITIVE MANUFACTURING STRATASYS INC (US) 2024-06-13 US disclosed
US-11939480-B2 Water dispersible sulfonated thermoplastic copolymer for use in additive manufacturing STRATASYS, INC. (US) 2024-03-26 US disclosed
US-20230330245-A1 ANTIBODY-EXATECAN CONJUGATES SYNAFFIX B.V. (NL) 2023-10-19 US disclosed
WO-2023192961-A2 LIGAND-PAYLOAD CONJUGATES PYXIS ONCOLOGY, INC. (US) 2023-10-05 WO disclosed
WO-2023171597-A1 HIGH-PURITY 4-(2-BROMOETHYL)BENZENESULFONIC ACID, HIGH-PURITY STYRENESULFONIC ACIDS DERIVED THEREFROM AND POLYMERS THEREOF, AND METHODS FOR PRODUCING SAME 東ソー・ファインケム株式会社 2023-09-14 WO disclosed
US-11459410-B2 High-purity amphipathic arylsulfonic acid amine salt vinyl monomer and copolymer thereof TOSOH FINECHEM CORPORATION (JP) 2022-10-04 US disclosed
CN-110997631-B High purity amphiphilic arylsulfonic acid amine salt vinyl monomers and (co) polymers thereof 东曹精细化工株式会社 2022-07-15 CN disclosed
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer CHISSO CORPORATION (JP) 2005-01-13 US disclosed
EP-0722959-B1 Highly oxygen-permeable heat-resistant material MENICON CO LTD (JP) 1998-04-08 EP disclosed
US-5587445-A Highly oxygen-permeable heat-resistant material MENICON CO., LTD. (JP) 1996-12-24 US disclosed
EP-0722959-A2 Highly oxygen-permeable heat-resistant material Menicon Co., Ltd. (JP) 1996-07-24 EP disclosed
EP-0393713-B1 Process for the preparation of N-substituted maleimides TOSOH CORP (JP) 1994-06-29 EP disclosed
EP-0376336-B1 N-substituted maleimide polymer composition NIPPON OILS & FATS CO LTD (JP) 1994-02-16 EP disclosed
US-5179162-A Polyoxymethylene glycol blend with a maleimide polymer NIPPON OIL & FATS CO., LTD. (JP) 1993-01-12 US disclosed
US-5087705-A Heating N-substituted maleamic acid monoester in presence of acid catalyst SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) 1992-02-11 US disclosed
EP-0393713-A1 Process for the preparation of N-substituted maleimides Tosoh Corporation (JP) 1990-10-24 EP disclosed
EP-0376336-A2 N-substituted maleimide polymer composition NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1990-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11459410-B2 High-purity amphipathic arylsulfonic acid amine salt vinyl monomer and copolymer thereof SLC7A1, ARSA, STS MGLL 3058/4885FAAH 1069/4885L3MBTL1 4594/4885
US-20230330245-A1 ANTIBODY-EXATECAN CONJUGATES ERBB3, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, IL23R MGLL 4664/4885FAAH 4450/4885L3MBTL1 558/4885
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer C1S, H1-4, H1-0 MGLL 4700/4885FAAH 4471/4885L3MBTL1 1418/4885
US-20250092171-A1 HIGH-PURITY 4-(2-BROMOETHYL)BENZENESULFONIC ACID, HIGH-PURITY STYRENESULFONIC ACID COMPOUND DERIVED THEREFROM, AND POLYMER THEREOF, AND METHODS FOR PRODUCING SAME BRPF1, WEE2, WEE1 MGLL 4545/4885FAAH 4723/4885L3MBTL1 2465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.