SCHEMBL1740710

SCHEMBL1740710

CCCCCCCCCCn1ncc2c(N)nccc21

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDR P35968 5/20 0.42
ADA P00813 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1743157 1.00 KDR (0.42) KDRADA
SCHEMBL28900816 0.88 ADORA2A (0.39)
SCHEMBL7212761 0.80 ADORA2A (0.36)
SCHEMBL309237 0.77 TLR8 (0.50)
SCHEMBL28813581 0.77 PDE4B (0.38)
SCHEMBL1741431 0.75 SIGMAR1 (0.57) KDR
SCHEMBL11899477 0.75 SIGMAR1 (0.57) KDR
SCHEMBL1740627 0.75 SIGMAR1 (0.57) KDR
SCHEMBL1740622 0.75 SIGMAR1 (0.57) KDR
Hydrochloric Acid SCHEMBL1741491 0.74 SIGMAR1 (0.56) KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2389436-A2 STEM CELL CULTURE METHODS ITI Scotland Limited (GB) 2011-11-30 EP disclosed
US-20110257911-A1 SYSTEMS AND METHODS FOR DETECTING CHANGES IN ENERGY USAGE IN A BUILDING JOHNSON CONTROLS TECHNOLOGY COMPANY 2011-10-20 US disclosed
WO-2010084300-A2 STEM CELL CULTURE METHODS ITI SCOTLAND LIMITED (GB) 2010-07-29 WO disclosed