Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29824715 | 0.78 | TNK2 (0.40) | NPC1UTS2RLMNA | |
| SCHEMBL1740710 | 0.77 | KDR (0.42) | — | |
| SCHEMBL1743157 | 0.77 | KDR (0.42) | — | |
| SCHEMBL30295640 | 0.75 | RXFP1 (0.41) | RXFP1LMNA | |
| SCHEMBL17873835 | 0.75 | RXFP1 (0.41) | RXFP1LMNA | |
| SCHEMBL21603424 | 0.74 | LMNA (0.48) | TSHRNPC1RXFP1UTS2RLMNA | |
| SCHEMBL21333168 | 0.74 | RECQL (0.53) | TSHRNPC1MPOPKMLMNA | |
| SCHEMBL13115663 | 0.73 | KMO (0.51) | PDE4BPDE4D | |
| SCHEMBL28900816 | 0.72 | ADORA2A (0.39) | NPC1 | |
| SCHEMBL958548 | 0.72 | CYP17A1 (0.48) | PKMLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077323-A1 | OGA INHIBITOR COMPOUNDS | Janssen Pharmaceutica NV (BE) | 2022-10-26 | — | — | EP | disclosed |
| CN-114867725-A | OGA inhibitor compounds | 詹森药业有限公司 | 2022-08-05 | — | — | CN | disclosed |