SCHEMBL1740865

SCHEMBL1740865

CC1=C(C)C(=O)CC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11132441 0.82
SCHEMBL11864997 0.79 ALDH1A1 (0.31)
SCHEMBL13713778 0.79
SCHEMBL9999455 0.77
Water SCHEMBL7649281 0.75 TYR (0.37)
SCHEMBL13402640 0.75
SCHEMBL17826992 0.69 TRIM24 (0.41)
SCHEMBL13402634 0.68
SCHEMBL13853999 0.67 UCHL1 (0.43)
SCHEMBL18160867 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170145058-A1 METHOD FOR TARGETED CONJUGATION OF PEPTIDES AND PROTEINS BY PAIRED C2 BRIDGING OF CYSTEINE AMINO ACIDS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2017-05-25 US disclosed
US-9051354-B2 Protein charge regulator and protein-encapsulating polymer micelle complex THE UNIVERSITY OF TOKYO (JP) 2015-06-09 US disclosed
US-8524732-B2 Substituted tetrahydroquinolines MERCK PATENT GMBH (DE) 2013-09-03 US disclosed
US-8163074-B2 Phase change inks containing colorant compounds XEROX CORPORATION (US) 2012-04-24 US disclosed
EP-2388297-A1 CURABLE COMPOSITION AND CURED OBJECT FORMED THEREFROM Kaneka Corporation (JP) 2011-11-23 EP disclosed
US-20110190458-A1 RE-MOULDABLE CROSS-LINKED RESIN, A COMPOSITION, A SUBSTITUTED FURAN, AND PROCESSES FOR PREPARING THE SAME RIJKSUNIVERSITEIT GRONINGEN (NL) 2011-08-04 US disclosed
US-7834215-B2 Unsymmetrically substituted phospholane catalysts EVONIK DEGUSSA GMBH (DE) 2010-11-16 US disclosed
US-20100022579-A1 SUBSTITUTED TETRAHYDROQUINOLINES Merck Patent Gesellschaft mit bescrankter Haftung (DE) 2010-01-28 US disclosed
US-7589215-B2 Bisphosphines as bidentate ligands DEGUSSA AG (DE) 2009-09-15 US disclosed
US-20090118519-A1 Production Method of Polycyclic Lactams SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-07 US disclosed
US-20080200695-A1 Unsymmetrically Substituted Phospholane Catalysts DEGUSSA GMBH (DE) 2008-08-21 US disclosed
US-7361786-B2 Bisphosphines as bidentate ligands DEGUSSA AG (DE) 2008-04-22 US disclosed
US-20070244211-A1 Crosslinkable poly(oxyalkylene)-containing polyamide prepolymers NOVARTIS AG (CH) 2007-10-18 US disclosed
US-20070179301-A1 BISPHOSPHINES AS BIDENTATE LIGANDS DEGUSSA AG (DE) 2007-08-02 US disclosed
US-20070149781-A1 Process for preparing bisphospholane ligands DEGUSSA AG (DE) 2007-06-28 US disclosed
US-20070123733-A1 BISPHOSPHINES AS BIDENTATE LIGANDS DEGUSSA AG (DE) 2007-05-31 US disclosed
WO-1995010261-A1 NOVEL CYCLOPENT-1-EN-3,5-DIONE COMPOUNDS AND COMPOSITIONS UNION CAMP CORPORATION (US) 1995-04-20 WO disclosed
US-5407910-A Floral fragrances UNION CAMP CORPORATION (US) 1995-04-18 US disclosed