SCHEMBL17409255

SCHEMBL17409255

CCC(C)(C)C(=O)Oc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.38
RAB9A P51151 5/20 0.38
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 3/20 0.38
MAPT P10636 3/20 0.38
HPGD P15428 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
POLB P06746 3/20 0.37
F2R P25116 1/20 0.35
LMNA P02545 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
IGF2BP2 Q9Y6M1 1/20 0.35
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
ELANE P08246 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8580605 0.86 NPC1 (0.43) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL29791013 0.86 NPC1 (0.43) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL29152914 0.84 NPC1 (0.42) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL17409169 0.83 NPC1 (0.49) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL28411781 0.82 NPC1 (0.44) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL13400676 0.82 F2R (0.35) MAPTPOLBF2RNPSR1L3MBTL1
SCHEMBL8360557 0.81 KDM4E (0.47) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL2777176 0.81 NPC1 (0.41) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL28547709 0.80 CA1 (0.54) NPC1RAB9AALDH1A1SMN1; SMN2KDM4E
SCHEMBL17548965 0.79 CA2 (0.50) ALDH1A1SMN1; SMN2MAPTTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160004154-A1 RADIATION-SENSITIVE COLORED COMPOSITIONS, CURED COLORED FILMS, COLOR FILTERS, PROCESSES FOR FORMING COLORED PATTERNS, PROCESSES FOR PREPARING COLOR FILTERS, SOLID-STATE IMAGE SENSORS AND LIQUID CRYSTAL DISPLAY DEVICES FUJIFILM CORPORATION (JP) 2016-01-07 US disclosed