SCHEMBL8580605

SCHEMBL8580605

CCC(=O)Oc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.43
RAB9A P51151 6/20 0.43
MAPT P10636 4/20 0.43
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 3/20 0.43
HPGD P15428 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
POLB P06746 2/20 0.41
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
LMNA P02545 1/20 0.39
KMT2A Q03164 2/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
IGF2BP2 Q9Y6M1 1/20 0.38
ELANE P08246 1/20 0.36
F2R P25116 1/20 0.36
PPARG P37231 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29791013 1.00 NPC1 (0.43) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL29152914 0.91 NPC1 (0.42) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL28411781 0.89 NPC1 (0.44) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL8376178 0.88 NR1H4 (0.36) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL17409255 0.86 NPC1 (0.38) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL8722027 0.84 NPC1 (0.39) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL8360557 0.83 KDM4E (0.47) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL2777176 0.83 NPC1 (0.41) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL30254806 0.82 NPC1 (0.38) NPC1RAB9AMAPTALDH1A1KDM4E
SCHEMBL28421751 0.81 KCNMA1 (0.41) NPC1RAB9AMAPTKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12569879-B2 Process for producing a multilayer coating comprising a sparkling coat layer and multilayer coating obtained from said process BASF COATINGS GMBH (DE) 2026-03-10 US disclosed
US-20260008920-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2026-01-08 US disclosed
US-12460099-B2 Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment THE PILOT INK CO., LTD. (JP) 2025-11-04 US disclosed
WO-2023114489-A9 MOISTURE-RESISTANT COMPOSITIONS FOR ROOF COATINGS HENRY COMPANY, LLC (US) 2024-10-10 WO disclosed
US-12055796-B2 Lens and method for manufacturing lens CARL ZEISS VISION INTERNATIONAL GMBH (DE) 2024-08-06 US disclosed
CN-118325210-A Ageing-resistant rubber material for sealing ring and preparation method thereof 扬州赛普润橡塑有限公司 2024-07-12 CN disclosed
CN-117820557-A Ultraviolet-resistant ABS material, preparation method thereof and packaging bottle 余姚市维航塑业有限公司 2024-04-05 CN disclosed
CN-114025888-B Method for producing a multilayer coating comprising a flash coating and multilayer coating obtained by said method 巴斯夫涂料有限公司 2023-07-25 CN disclosed
WO-2023114489-A1 MOISTURE-RESISTANT COMPOSITIONS FOR ROOF COATINGS HENRY COMPANY, LLC (US) 2023-06-22 WO disclosed
US-20230159748-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2023-05-25 US disclosed
US-20220169919-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2022-06-02 US disclosed
US-11339285-B2 Multilayer body TEIJIN LIMITED (JP) 2022-05-24 US disclosed
US-11285710-B2 Multilayer body TEIJIN LIMITED (JP) 2022-03-29 US disclosed
CN-114025888-A Method for producing a multilayer coating comprising a iridescent coating and multilayer coating obtained by said method 巴斯夫涂料有限公司 2022-02-08 CN disclosed
CN-114026184-A Resistant 2K-PUR coatings 科思创知识产权两合公司 2022-02-08 CN disclosed
EP-3819119-A1 DECORATIVE FILM, DECORATION METHOD, DECORATIVE MOLDED BODY PRODUCTION METHOD, AND DECORATIVE MOLDED FILM FUJIFILM Corporation (JP) 2021-05-12 EP disclosed
US-20210070022-A1 DECORATIVE FILM, DECORATION METHOD, METHOD FOR MANUFACTURING DECORATIVE MOLDED ARTICLE, AND DECORATIVE MOLDED FILM FUJIFILM CORPORATION (JP) 2021-03-11 US disclosed
EP-3452528-A1 METHOD FOR PRODUCING A POLYISOCYANURATE COMPOSITE MATERIAL Covestro Deutschland AG (DE) 2019-03-13 EP disclosed
EP-3452529-A1 METHOD FOR PRODUCING A POLYISOCYANURATE COMPOSITE MATERIAL Covestro Deutschland AG (DE) 2019-03-13 EP disclosed
US-5843339-A Phosphites and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008920-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF NOP2, CCT2, RPL8 NPC1 2405/4885RAB9A 3900/4885MAPT 2407/4885
US-12569879-B2 Process for producing a multilayer coating comprising a sparkling coat layer and multilayer coating obtained from said process C9, COL2A1, F13A1 NPC1 1076/4885RAB9A 903/4885MAPT 340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.