SCHEMBL1740944

SCHEMBL1740944

C=Cn1cncc2ncnc1-2

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.34
LMNA P02545 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6639614 0.69 LTA4H (0.36) LTA4H
SCHEMBL1535169 0.69 LTA4H (0.36) LTA4H
SCHEMBL9055137 0.64
SCHEMBL4245619 0.64
SCHEMBL4896472 0.60
SCHEMBL434034 0.59 FDPS (0.44) LTA4HLMNATDP1
SCHEMBL19970312 0.59
SCHEMBL20798989 0.58
SCHEMBL820304 0.58 HDAC6 (0.38) LTA4H
SCHEMBL19970315 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2390257-A1 2'-fluoronucleosides Emory University (US) 2011-11-30 EP disclosed
US-20110256952-A1 GOLF CLUB, SHAFT REPLACING METHOD AND HEAD REPLACING METHOD BRIDGESTONE SPORTS CO., LTD. (JP) 2011-10-20 US disclosed