Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 14/20 | 1.00 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17409485 | 0.92 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409454 | 0.90 | KDR (1.00) | KDRPDGFRBKIT | |
| SCHEMBL17409487 | 0.88 | KDR (1.00) | KDRPDGFRBKITFGFR1BRAF | |
| SCHEMBL17409477 | 0.86 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409488 | 0.83 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17424247 | 0.82 | KDR (0.80) | KDRPDGFRB | |
| SCHEMBL17409459 | 0.81 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409486 | 0.79 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL3348249 | 0.78 | KDR (0.64) | KDRPDGFRBKIT | |
| SCHEMBL17409473 | 0.77 | KDR (1.00) | KDRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | claimed |
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |