Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 19/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 14/20 | 0.65 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17424247 | 0.89 | KDR (0.80) | KDRPDGFRB | |
| SCHEMBL17409455 | 0.79 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409475 | 0.79 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409489 | 0.76 | KDR (0.60) | KDRPDGFRB | |
| SCHEMBL17409452 | 0.75 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17424510 | 0.74 | KDR (0.82) | KDRPDGFRB | |
| SCHEMBL17424509 | 0.71 | KDR (0.82) | KDRPDGFRB | |
| SCHEMBL17409472 | 0.71 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409474 | 0.69 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409486 | 0.69 | KDR (1.00) | KDRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | claimed |
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |