Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 12/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.55 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17424245 | 0.78 | KDR (0.51) | KDRPDGFRBPDE10A | |
| SCHEMBL17409490 | 0.76 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17409449 | 0.76 | KDR (0.58) | KDRPDGFRBAPP | |
| SCHEMBL17409455 | 0.72 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL17424247 | 0.69 | KDR (0.80) | KDRPDGFRB | |
| SCHEMBL12673757 | 0.66 | DYRK1A (0.41) | KDRPDGFRB | |
| SCHEMBL16409613 | 0.66 | PIK3CG (0.40) | KDRPDGFRB | |
| SCHEMBL1302985 | 0.66 | KDM4E (0.46) | KDRPDGFRB | |
| SCHEMBL2514258 | 0.66 | PIK3CG (0.40) | KDRPDGFRB | |
| SCHEMBL9611200 | 0.65 | APP (1.00) | APPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-9233968-B1 | Kinase inhibitors | ALLERGAN, INC. (US) | 2016-01-12 | — | — | US | disclosed |