Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 8/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18858449 | 1.00 | ALDH1A1 (0.75) | ALDH1A1LMNAHSD17B10KMT2AKDM4E | |
| SCHEMBL4077176 | 0.78 | ALDH1A1 (0.69) | ALDH1A1LMNAKMT2AKDM4EMEN1 | |
| SCHEMBL8689527 | 0.78 | ALDH1A1 (0.69) | ALDH1A1LMNAKMT2AKDM4EMEN1 | |
| SCHEMBL8795558 | 0.77 | ALOX15 (0.68) | ALDH1A1CYP1A2HPGDXBP1CYP2C19 | |
| SCHEMBL1504139 | 0.77 | ALOX15 (0.61) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL1503856 | 0.76 | ALOX15 (0.81) | ALDH1A1LMNAKMT2AKDM4EMEN1 | |
| SCHEMBL29954955 | 0.76 | ALOX15 (0.81) | ALDH1A1LMNAKMT2AKDM4EMEN1 | |
| SCHEMBL1503892 | 0.76 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2AKDM4EMEN1 | |
| SCHEMBL12496609 | 0.76 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2AKDM4EMEN1 | |
| SCHEMBL4317810 | 0.76 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016000827-A1 | AZEPANYL-DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME WITH ANTIPARASITIC ACTIVITY | MERCK PATENT GMBH (DE) | 2016-01-07 | — | — | WO | disclosed |