Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317002 | 0.89 | — | — | |
| SCHEMBL7625193 | 0.89 | — | — | |
| SCHEMBL9188138 | 0.81 | TSHR (0.35) | TSHR | |
| SCHEMBL16975982 | 0.78 | — | — | |
| SCHEMBL8383500 | 0.77 | SMN1; SMN2 (0.38) | TSHR | |
| SCHEMBL15838935 | 0.76 | TP53 (0.46) | — | |
| SCHEMBL6033814 | 0.75 | ESR1 (0.31) | — | |
| SCHEMBL18377366 | 0.73 | — | — | |
| SCHEMBL27774625 | 0.73 | ALDH1A1 (0.39) | EPHX2 | |
| SCHEMBL23315727 | 0.72 | KDM1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016004272-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS LLC (US) | 2016-01-07 | — | — | WO | disclosed |