SCHEMBL17410890

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Iruplinalkib SCHEMBL30297159	0.89	ALK (1.00)	ALKEGFRINSRIGF1RCHEK1
	Iruplinalkib SCHEMBL30195062	0.89	ALK (1.00)	ALKEGFRINSRIGF1RCHEK1
	Iruplinalkib SCHEMBL17411099	0.89	ALK (1.00)	ALKEGFRINSRIGF1RCHEK1
	SCHEMBL11916622	0.89	ALK (0.80)	ALKEGFRINSRIGF1RCHEK1
	SCHEMBL17410900	0.87	ALK (1.00)	ALKEGFRINSRIGF1RCHEK1
	SCHEMBL17410973	0.84	ALK (0.90)	ALKEGFRINSRIGF1RCHEK1
	SCHEMBL17410897	0.84	ALK (0.79)	ALKEGFRINSRIGF1R
	SCHEMBL27270881	0.83	ALK (0.87)	ALKEGFRINSRIGF1RCHEK1
	SCHEMBL17410982	0.83	ALK (1.00)	ALKEGFRINSRIGF1RCHEK1
	SCHEMBL24940073	0.82	ALK (0.77)	ALKEGFRINSRIGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.