Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 13/20 | 0.61 |
| ▸ | LPL | P06858 | 12/20 | 0.61 |
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2265622 | 0.81 | LIPG (0.64) | LIPGLPLCA1CA2CA9 | |
| SCHEMBL28389622 | 0.81 | LIPG (0.88) | LIPGLPLCA1CA2CA9 | |
| SCHEMBL19858597 | 0.80 | LIPG (0.85) | LIPGLPLCA1CA2CA9 | |
| SCHEMBL22722776 | 0.80 | LIPG (0.85) | LIPGLPLCA1CA2CA9 | |
| SCHEMBL24608995 | 0.79 | LIPG (0.83) | LIPGLPLCA1CA2CA9 | |
| SCHEMBL2707320 | 0.79 | LIPG (0.83) | LIPGLPLCA1CA2CA9 | |
| SCHEMBL13855173 | 0.79 | LIPG (0.70) | LIPGLPLCA1CA2CA9 | |
| SCHEMBL4813824 | 0.78 | LIPG (0.69) | LIPGLPLCA1CA2CA9 | |
| SCHEMBL23750301 | 0.78 | LIPG (0.69) | LIPGLPLCA1CA2CA9 | |
| SCHEMBL30638490 | 0.77 | LIPG (0.67) | LIPGLPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549010-B | Preparation and application of compound with AMPK (AMPK) agonistic activity and prodrug thereof | 中国科学院上海药物研究所 | 2023-10-20 | — | — | CN | disclosed |
| WO-2016001224-A1 | NOVEL ACTIVATORS OF AMP-ACTIVATED PROTEIN KINASES | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2016-01-07 | — | — | WO | disclosed |