SCHEMBL4813824

SCHEMBL4813824

CC1(C)OB(c2ccc(-c3ccc(O)cc3)cc2)OC1(C)C

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 13/20 0.69
LPL P06858 12/20 0.69
F11 P03951 2/20 0.47
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 2/20 0.45
CA12 O43570 1/20 0.45
CA3 P07451 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA5A P35218 1/20 0.45
CA7 P43166 1/20 0.45
CA14 Q9ULX7 1/20 0.45
CA5B Q9Y2D0 1/20 0.45
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
P4HB P07237 1/20 0.42
F2 P00734 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23750301 1.00 LIPG (0.69) LIPGLPLF11CA1CA2
SCHEMBL102562 0.94 LIPG (0.59) LIPGLPLF11CA1CA2
SCHEMBL2707320 0.89 LIPG (0.83) LIPGLPLF11CA1CA2
SCHEMBL24608995 0.89 LIPG (0.83) LIPGLPLF11CA1CA2
SCHEMBL17952428 0.84 LIPG (0.50) LIPGLPLF11ESR1ESR2
SCHEMBL28389622 0.83 LIPG (0.88) LIPGLPLF11CA1CA2
SCHEMBL12681706 0.83 LIPG (0.74) LIPGLPLF11CA1CA2
SCHEMBL15476363 0.83 P4HB (0.56) LIPGLPLF11CA1CA2
SCHEMBL19729193 0.83 LIPG (0.69) LIPGLPLF11CA1CA2
SCHEMBL19729194 0.83 LPL (0.49) LIPGLPLF11CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4667509-A1 POLYMER, ELECTROLYTE MATERIAL, ELECTROLYTE MEMBRANE, ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, SOLID POLYMER FUEL CELL, AND SOLID POLYMER WATER ELECTROLYSIS DEVICE Tosoh Corporation (JP) 2025-12-24 EP disclosed
WO-2024204267-A1 POLYMER, ELECTROLYTE MATERIAL, ELECTROLYTE MEMBRANE, ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, SOLID POLYMER FUEL CELL, AND SOLID POLYMER WATER ELECTROLYSIS DEVICE 東ソー株式会社 2024-10-03 WO disclosed
WO-2024153107-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND USE THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE 北京鼎材科技有限公司 2024-07-25 WO disclosed
CN-113549010-B Preparation and application of compound with AMPK (AMPK) agonistic activity and prodrug thereof 中国科学院上海药物研究所 2023-10-20 CN disclosed
CN-115417823-A Preparation method of pyrimidine biphenyl aromatic ring compound 上海泰坦科技股份有限公司 2022-12-02 CN disclosed
CN-113549010-A Preparation and application of compound with AMPK agonistic activity and prodrug thereof 中国科学院上海药物研究所 2021-10-26 CN disclosed
US-10478425-B2 5-phenylazaindole derivative having AMPK-activating activity SHIONOGI & CO., LTD. (JP) 2019-11-19 US disclosed
EP-3421467-A1 5-PHENYLAZAINDOLE DERIVATIVE HAVING AMPK ACTIVATING EFFECT Shionogi & Co., Ltd (JP) 2019-01-02 EP disclosed
WO-2017146186-A1 5-PHENYLAZAINDOLE DERIVATIVE HAVING AMPK ACTIVATING EFFECT 塩野義製薬株式会社 2017-08-31 WO disclosed
US-7320986-B2 Fused tri and tetra-cyclic pyrazole kinase inhibitors ABBOTT LABORTORIES (US) 2008-01-22 US disclosed
US-20040259904-A1 Fused tri and tetra-cyclic pyrazole kinase inhibitors ABBVIE INC. 2004-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040259904-A1 Fused tri and tetra-cyclic pyrazole kinase inhibitors TK1, MAP3K19, MAP3K20 LIPG 2720/4885LPL 4512/4885F11 2252/4885
US-10478425-B2 5-phenylazaindole derivative having AMPK-activating activity PRKAG2, PRKAG1, PRKAB2 LIPG 2637/4885LPL 404/4885F11 4862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.