SCHEMBL1741192

SCHEMBL1741192

CCCC(O)C(C)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1741194 1.00 LMNA (0.32) LMNACA2
SCHEMBL1740625 0.87 SPHK1 (0.43) LMNACA2
SCHEMBL1742920 0.86 SPHK1 (0.46) LMNACA2
SCHEMBL1740518 0.86 SPHK1 (0.46) LMNACA2
SCHEMBL11898965 0.86 SPHK1 (0.46) LMNACA2
SCHEMBL31480605 0.84 TSHR (0.31)
SCHEMBL13573090 0.84 TSHR (0.31)
SCHEMBL17707939 0.78
SCHEMBL4995784 0.78 CA2 (0.32) CA2
SCHEMBL1742940 0.77 CA2 (0.30) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2389436-A2 STEM CELL CULTURE METHODS ITI Scotland Limited (GB) 2011-11-30 EP disclosed
US-20110257911-A1 SYSTEMS AND METHODS FOR DETECTING CHANGES IN ENERGY USAGE IN A BUILDING JOHNSON CONTROLS TECHNOLOGY COMPANY 2011-10-20 US disclosed
WO-2010084300-A2 STEM CELL CULTURE METHODS ITI SCOTLAND LIMITED (GB) 2010-07-29 WO disclosed