Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 3/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243499 | 0.90 | MEN1 (0.67) | TNFNOD1MEN1MAPTKMT2A | |
| SCHEMBL29617471 | 0.90 | MEN1 (0.67) | TNFNOD1MEN1MAPTKMT2A | |
| SCHEMBL11339110 | 0.81 | MEN1 (0.68) | TNFNOD1MEN1MAPTKMT2A | |
| SCHEMBL16138724 | 0.80 | RAB9A (0.49) | TNFNOD1MEN1MAPTKMT2A | |
| SCHEMBL24460157 | 0.79 | MEN1 (0.55) | TNFNOD1MEN1MAPTKMT2A | |
| SCHEMBL18341404 | 0.79 | P2RX1 (0.65) | TNFNOD1MEN1MAPTKMT2A | |
| SCHEMBL29617489 | 0.79 | P2RX1 (0.65) | TNFNOD1MEN1MAPTKMT2A | |
| SCHEMBL17411509 | 0.78 | RAB9A (0.48) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL16138819 | 0.78 | ALDH1A1 (0.51) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL24460193 | 0.76 | MAPT (0.67) | TNFNOD1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016004363-A2 | METHODS AND COMPOSITIONS FOR TREATING OBESITY, PREVENTING WEIGHT GAIN, PROMOTING WEIGHT LOSS, PROMOTING SLIMMING, OR TREATING OR PREVENTING THE DEVELOPMENT OF DIABETES | NAN Global, LLC (US) | 2016-01-07 | — | — | WO | disclosed |