SCHEMBL17412428

SCHEMBL17412428

Clc1cc(-c2cccc3ccccc23)nc(-c2ccc3ccccc3c2)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 2/20 0.46
HSP90AA1 P07900 1/20 0.42
HSP90AB1 P08238 1/20 0.42
ALDH1A1 P00352 3/20 0.41
CYP1A2 P05177 2/20 0.41
KDM4E B2RXH2 2/20 0.41
ATM Q13315 2/20 0.41
HSD17B10 Q99714 2/20 0.41
CYP2C19 P33261 1/20 0.41
RAB9A P51151 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP2A6 P11509 1/20 0.38
GSTP1 P09211 1/20 0.38
BMX P51813 1/20 0.38
ENPP3 O14638 1/20 0.38
ENPP1 P22413 1/20 0.38
MAOB P27338 1/20 0.38
AURKA O14965 1/20 0.38
AURKB Q96GD4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17970002 0.89 PIM1 (0.51) PIM1ALDH1A1CYP1A2KDM4EATM
SCHEMBL21701674 0.86 LMNA (0.51) HSP90AA1HSP90AB1ALDH1A1CYP1A2KDM4E
SCHEMBL10051296 0.85 PIM1 (0.51) PIM1ALDH1A1CYP1A2KDM4EMEN1
SCHEMBL17412408 0.84 HSP90AA1 (0.49) HSP90AA1HSP90AB1ALDH1A1CYP1A2KDM4E
SCHEMBL24212279 0.84 LMNA (0.46) HSP90AA1HSP90AB1ALDH1A1CYP1A2KDM4E
SCHEMBL17969978 0.84 PIM1 (0.50) PIM1ALDH1A1CYP1A2KDM4ECYP2C19
SCHEMBL17970007 0.83 CYP1A2 (0.54) PIM1ALDH1A1CYP1A2KDM4ECYP2C19
SCHEMBL17412387 0.82 CYP1A2 (0.53) HSP90AA1HSP90AB1ALDH1A1CYP1A2KDM4E
SCHEMBL30934026 0.82 CYP1A2 (0.53) HSP90AA1HSP90AB1ALDH1A1CYP1A2KDM4E
SCHEMBL16805051 0.82 PIM1 (0.46) PIM1ALDH1A1CYP1A2KDM4ECYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016003225-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2016-01-07 WO disclosed