SCHEMBL21701674

SCHEMBL21701674

Clc1cc(-c2cccc3ccccc23)nc(-c2ccccc2)n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.51
KDM4E B2RXH2 4/20 0.50
MAPT P10636 3/20 0.50
ALDH1A1 P00352 3/20 0.50
HSD17B10 Q99714 3/20 0.50
MAPK1 P28482 3/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ATM Q13315 2/20 0.50
HPGD P15428 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
HSP90AA1 P07900 2/20 0.45
HSP90AB1 P08238 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22249515 0.89 KDM4E (0.47) LMNAKDM4EMAPTALDH1A1HSD17B10
SCHEMBL17412389 0.89 KDM4E (0.47) LMNAKDM4EMAPTALDH1A1HSD17B10
SCHEMBL17412408 0.88 HSP90AA1 (0.49) KDM4EMAPTALDH1A1HSD17B10MAPK1
SCHEMBL12306184 0.88 ALDH1A1 (0.57) LMNAKDM4EMAPTALDH1A1HSD17B10
SCHEMBL17969914 0.88 ALDH1A1 (0.57) LMNAKDM4EMAPTALDH1A1HSD17B10
SCHEMBL24212279 0.88 LMNA (0.46) LMNAKDM4EMAPTALDH1A1HSD17B10
SCHEMBL17412397 0.88 KDM4E (0.44) LMNAKDM4EMAPTALDH1A1HSD17B10
SCHEMBL29750648 0.87 KDM4E (0.51) LMNAKDM4EMAPTALDH1A1HSD17B10
SCHEMBL17412427 0.87 KDM4E (0.51) LMNAKDM4EMAPTALDH1A1HSD17B10
SCHEMBL25649590 0.87 LMNA (0.54) LMNAKDM4EMAPTALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4600325-B1 ORGANIC LIGHT-EMITTING COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SOLUS ADVANCED MATERIALS CO LTD (KR) 2026-04-29 EP disclosed
EP-4600325-A1 ORGANIC LIGHT-EMITTING COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME Solus Advanced Materials Co., Ltd. (KR) 2025-08-13 EP disclosed
WO-2025135308-A1 ORGANIC LIGHT-EMITTING COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 솔루스첨단소재 주식회사 2025-06-26 WO disclosed
US-20220020938-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2022-01-20 US disclosed
US-20200048230-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT INCLUDING SAME LG CHEM, LTD. (KR) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048230-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT INCLUDING SAME CRY1, CRY2, CYP1A1 LMNA 3400/4885KDM4E 2566/4885MAPT 1552/4885
US-20220020938-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF NFE2L2, ETV6, ESR1 LMNA 2684/4885KDM4E 482/4885MAPT 1051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.