Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17413642 | 0.88 | NPC1 (0.49) | HPGDCYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL17849119 | 0.87 | NPC1 (0.53) | HPGDCYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL17232535 | 0.87 | HPGD (0.45) | HPGDCYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL18932459 | 0.87 | CYP1A2 (0.53) | HPGDCYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL15786300 | 0.86 | HPGD (0.44) | HPGDCYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL17413641 | 0.85 | HPGD (0.46) | HPGDCYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL17397904 | 0.84 | POLB (0.53) | HPGDCYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL17413567 | 0.81 | CYP1A2 (0.47) | HPGDCYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL18932461 | 0.77 | CYP1A2 (0.66) | HPGDCYP1A2CYP2C9CYP2C19NPC1 | |
| SCHEMBL20386014 | 0.77 | POLB (0.50) | HPGDCYP1A2CYP2C9CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988347-B2 | Herbicidally active arylcarboxylic acid amides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-05 | — | — | US | disclosed |
| US-9988347-B2 | Herbicidally active arylcarboxylic acid amides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-05 | — | — | US | disclosed |
| EP-3160945-B1 | HERBICIDAL ARYLCARBOXYLIC ACID AMIDES | BAYER CROPSCIENCE AG (DE) | 2018-01-31 | — | — | EP | disclosed |
| US-20170158629-A1 | Herbicidally Active Arylcarboxylic Acid Amides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-06-08 | — | — | US | disclosed |
| US-20170158629-A1 | Herbicidally Active Arylcarboxylic Acid Amides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-06-08 | — | — | US | disclosed |
| WO-2016001073-A1 | HERBICIDALLY ACTIVE ARYLCARBOXYLIC ACID AMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158629-A1 | Herbicidally Active Arylcarboxylic Acid Amides | DDT, AADAC, AOX1 | HPGD 1492/4885CYP1A2 49/4885CYP2C9 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.