Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17413644 | 0.87 | HPGD (0.48) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17413642 | 0.82 | NPC1 (0.49) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18932459 | 0.78 | CYP1A2 (0.53) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17232535 | 0.77 | HPGD (0.45) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17410931 | 0.76 | POLB (0.48) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15786300 | 0.76 | HPGD (0.44) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17413641 | 0.75 | HPGD (0.46) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24782395 | 0.73 | CYP1A2 (0.44) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17413567 | 0.73 | CYP1A2 (0.47) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15212580 | 0.72 | POLB (0.46) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9371315-B2 | N-(tetrazol-5-yl)- and N-(triazol-5-yl)arylcarboxamide salts and use thereof as herbicides | BAYER CROPSCIENCE AG (DE) | 2016-06-21 | — | — | US | disclosed |