Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 2/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1741649 | 0.69 | CCNB2 (0.39) | TYMPFGFR1FGFR4 | |
| SCHEMBL11899618 | 0.69 | CCNB2 (0.39) | — | |
| SCHEMBL11900412 | 0.69 | CCNB2 (0.39) | TYMPFGFR1FGFR4 | |
| SCHEMBL2875474 | 0.69 | CCNB2 (0.39) | — | |
| SCHEMBL1741159 | 0.68 | PDE2A (0.36) | PI4KAPI4K2BPI4K2API4KBFGFR1 | |
| SCHEMBL11899186 | 0.68 | ADA (0.39) | PI4KAPI4K2BPI4K2API4KBFDPS | |
| SCHEMBL1741202 | 0.68 | PDE2A (0.36) | PI4KAPI4K2BPI4K2API4KBFGFR1 | |
| SCHEMBL1741206 | 0.68 | PDE2A (0.36) | PI4KAPI4K2BPI4K2API4KBFGFR1 | |
| SCHEMBL1741157 | 0.68 | PDE2A (0.36) | PI4KAPI4K2BPI4K2API4KBFGFR1 | |
| SCHEMBL21126195 | 0.65 | PI4KA (0.64) | PI4KAPI4K2BPI4K2API4KBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389436-A2 | STEM CELL CULTURE METHODS | ITI Scotland Limited (GB) | 2011-11-30 | — | — | EP | disclosed |
| US-20110257911-A1 | SYSTEMS AND METHODS FOR DETECTING CHANGES IN ENERGY USAGE IN A BUILDING | JOHNSON CONTROLS TECHNOLOGY COMPANY | 2011-10-20 | — | — | US | disclosed |
| WO-2010084300-A2 | STEM CELL CULTURE METHODS | ITI SCOTLAND LIMITED (GB) | 2010-07-29 | — | — | WO | disclosed |