Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 4/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17637941 | 0.92 | APEX1 (0.55) | MAPTPOLBPKMAPEX1CTDSP1 | |
| SCHEMBL14140626 | 0.90 | APEX1 (0.58) | MAPTPOLBPKMAPEX1CTDSP1 | |
| SCHEMBL18217887 | 0.87 | LMNA (0.55) | MAPTGAALMNAKMT2AALDH1A1 | |
| SCHEMBL10000040 | 0.86 | POLB (0.37) | MAPTPOLBPKMAPEX1CTDSP1 | |
| SCHEMBL21184203 | 0.78 | LMNA (0.64) | POLBAPEX1CTDSP1L3MBTL1MAPK1 | |
| SCHEMBL3148846 | 0.78 | ALDH1A1 (0.50) | MAPTPOLBL3MBTL1MAPK1GAA | |
| SCHEMBL1397921 | 0.77 | APEX1 (0.67) | MAPTPOLBAPEX1CTDSP1L3MBTL1 | |
| SCHEMBL29364883 | 0.77 | APEX1 (0.67) | MAPTPOLBAPEX1CTDSP1L3MBTL1 | |
| SCHEMBL65212 | 0.77 | APEX1 (0.67) | MAPTPOLBAPEX1CTDSP1L3MBTL1 | |
| SCHEMBL29394064 | 0.77 | APEX1 (0.67) | MAPTPOLBAPEX1CTDSP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160001528-A1 | ELECTRICAL COMPONENT | DENSO CORPORATION (JP) | 2016-01-07 | — | — | US | disclosed |
| US-20160001528-A1 | ELECTRICAL COMPONENT | DENSO CORPORATION (JP) | 2016-01-07 | — | — | US | disclosed |