SCHEMBL17414243

SCHEMBL17414243

OCc1ccc(C(Cl)(Cl)Cl)c(F)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.51
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39
RECQL P46063 1/20 0.34
PTGDR2 Q9Y5Y4 2/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PDK2 Q15119 1/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
DAO P14920 1/20 0.33
PRSS1 P07477 2/20 0.32
PRSS2 P07478 2/20 0.32
PRSS3 P35030 2/20 0.32
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
ENPP2 Q13822 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17414234 0.86 KIF11 (0.44) KIF11CYP4F2CYP4A11RECQLPTGDR2
SCHEMBL10969543 0.82 KIF11 (0.37) KIF11CYP3A4TSHRMAPK1TDP1
SCHEMBL92971 0.82 KIF11 (0.73) KIF11CYP4F2CYP4A11PDK2DAO
SCHEMBL31490875 0.78 RXRA (0.51) TSHRTDP1RXRARXRBRXRG
SCHEMBL27595825 0.76 KIF11 (0.51) KIF11CYP4F2CYP4A11PTGDR2PDK2
SCHEMBL12490262 0.74 KIF11 (0.50) KIF11CYP4F2CYP4A11PDK2DAO
SCHEMBL93021 0.73 CYP4F2 (0.50) KIF11CYP4F2CYP4A11PTGDR2TSHR
SCHEMBL12490260 0.73 KIF11 (0.49) KIF11CYP4F2CYP4A11PDK2HSD17B1
SCHEMBL17696934 0.72 KIF11 (0.47) KIF11CYP3A4TSHRMAPK1TDP1
SCHEMBL31412508 0.72 MAPT (0.45) KIF11CYP4F2CYP4A11RECQLPTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9856732-B2 Tracers RESTRACK AS (NO) 2018-01-02 US disclosed
EP-2935508-B1 TRACERS RESTRACK AS (NO) 2017-02-15 EP disclosed
US-20160003040-A1 Tracers Resman Technology AS (NO) 2016-01-07 US disclosed
US-20160003040-A1 Tracers Resman Technology AS (NO) 2016-01-07 US disclosed