Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.55 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959771 | 0.91 | PLK1 (0.64) | PLK1HSD17B1HSD17B2KDM4EGAA | |
| SCHEMBL12430522 | 0.80 | PLK1 (0.56) | PLK1HSD17B1HSD17B2KDM4EGAA | |
| SCHEMBL12430488 | 0.80 | PLK1 (0.56) | PLK1HSD17B1HSD17B2KDM4EGAA | |
| SCHEMBL12852634 | 0.79 | PLK1 (0.55) | PLK1HSD17B1HSD17B2KDM4EGAA | |
| SCHEMBL28131235 | 0.79 | PLK1 (0.55) | PLK1HSD17B1HSD17B2KDM4EGAA | |
| SCHEMBL19993570 | 0.79 | TUBB4A (0.61) | PLK1HSD17B1HSD17B2KDM4EGAA | |
| SCHEMBL2590130 | 0.79 | PLK1 (0.55) | PLK1HSD17B1HSD17B2KDM4EGAA | |
| SCHEMBL20145771 | 0.78 | PLK1 (0.50) | PLK1HSD17B1HSD17B2KDM4EGAA | |
| SCHEMBL17414595 | 0.78 | PLK1 (0.55) | PLK1 | |
| SCHEMBL9637773 | 0.77 | KDM4E (0.63) | KDM4EGAAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016004093-A2 | THERAPEUTIC COMPOSITIONS INCLUDING GALECTIN-3 INHIBITORS AND USES THEREOF | STEALTH BIOTHERAPEUTICS CORP (MC) | 2016-01-07 | — | — | WO | disclosed |