Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PLK1 | P53350 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25659599 | 0.95 | MAPT (0.55) | MAPTPLA2G2AKMT2APLK1RAB9A | |
| SCHEMBL19999965 | 0.91 | MAPT (0.55) | MAPTPLA2G2AKMT2APLK1RAB9A | |
| SCHEMBL11171580 | 0.91 | KDM4E (0.50) | MAPTKMT2APLK1RAB9AKDM4E | |
| SCHEMBL3176817 | 0.88 | KDM4E (0.54) | MAPTKMT2APLK1RAB9AKDM4E | |
| SCHEMBL5222156 | 0.86 | MAPT (0.50) | MAPTPLA2G2AKMT2APLK1RAB9A | |
| SCHEMBL2650746 | 0.85 | CA12 (0.59) | MAPTPLA2G2AKMT2APLK1RAB9A | |
| SCHEMBL3858281 | 0.85 | PLA2G2A (0.59) | MAPTPLA2G2AKMT2APLK1RAB9A | |
| SCHEMBL16898021 | 0.85 | NOTUM (0.50) | MAPTPLA2G2AKMT2APLK1RAB9A | |
| SCHEMBL731189 | 0.84 | MAPT (0.47) | MAPTKMT2APLK1RAB9AKDM4E | |
| SCHEMBL5225611 | 0.84 | ALDH1A1 (0.49) | MAPTPLA2G2AKMT2APLK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016004093-A2 | THERAPEUTIC COMPOSITIONS INCLUDING GALECTIN-3 INHIBITORS AND USES THEREOF | STEALTH BIOTHERAPEUTICS CORP (MC) | 2016-01-07 | — | — | WO | disclosed |