Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GYS1 | P13807 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17414642 | 0.91 | POLB (0.48) | MAPTNPC1RAB9AL3MBTL1POLB | |
| SCHEMBL17414635 | 0.85 | POLB (0.51) | MAPTNPC1RAB9AL3MBTL1POLB | |
| SCHEMBL17414665 | 0.82 | POLB (0.41) | MAPTNPC1RAB9AL3MBTL1POLB | |
| SCHEMBL17414634 | 0.80 | GYS1 (0.47) | L3MBTL1POLBGYS1 | |
| SCHEMBL17414633 | 0.80 | GYS1 (0.45) | L3MBTL1POLBGYS1 | |
| SCHEMBL17414648 | 0.79 | POLB (0.38) | MAPTNPC1RAB9AL3MBTL1POLB | |
| SCHEMBL17414656 | 0.79 | GYS1 (0.47) | MAPTNPC1RAB9AL3MBTL1POLB | |
| SCHEMBL17414643 | 0.78 | GYS1 (0.46) | MAPTNPC1RAB9AL3MBTL1POLB | |
| SCHEMBL17414663 | 0.77 | GYS1 (0.40) | MAPTNPC1RAB9AL3MBTL1POLB | |
| SCHEMBL17414644 | 0.77 | GYS1 (0.47) | MAPTNPC1RAB9AL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016002853-A1 | MEDICINAL COMPOSITION FOR TREATING DIABETES | 味の素株式会社 | 2016-01-07 | — | — | WO | disclosed |