Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17414679 | 0.92 | GYS1 (0.50) | GYS1MAPTNPC1RAB9AHSP90AA1 | |
| SCHEMBL17414643 | 0.83 | GYS1 (0.46) | GYS1MAPTNPC1RAB9AHSP90AA1 | |
| SCHEMBL17414644 | 0.83 | GYS1 (0.47) | GYS1MAPTNPC1RAB9AHSP90AA1 | |
| SCHEMBL17414649 | 0.81 | GYS1 (0.47) | GYS1MAPTNPC1RAB9AHSP90AA1 | |
| SCHEMBL17414673 | 0.80 | GYS1 (0.49) | GYS1MAPTNPC1RAB9AHSP90AA1 | |
| SCHEMBL17414636 | 0.79 | MAPT (0.48) | GYS1MAPTNPC1RAB9AHSP90AA1 | |
| SCHEMBL17414635 | 0.78 | POLB (0.51) | GYS1MAPTNPC1RAB9AHSP90AA1 | |
| SCHEMBL17414661 | 0.77 | GYS1 (0.52) | GYS1MAPTNPC1RAB9AHSP90AA1 | |
| SCHEMBL16224780 | 0.76 | GYS1 (0.70) | GYS1 | |
| SCHEMBL17414637 | 0.75 | GYS1 (0.49) | GYS1MAPTNPC1RAB9AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016002853-A1 | MEDICINAL COMPOSITION FOR TREATING DIABETES | 味の素株式会社 | 2016-01-07 | — | — | WO | disclosed |