SCHEMBL17414845

SCHEMBL17414845

C[Si](C)(O)c1cccc([Si](C)(C)O)c1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
ACHE P22303 3/20 0.36
NR1I2 O75469 3/20 0.34
NR1H2 P55055 2/20 0.33
NR1H3 Q13133 2/20 0.33
CCR1 P32246 1/20 0.32
CCR8 P51685 1/20 0.32
CA12 O43570 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CA2 P00918 1/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15677723 0.85 ACHE (0.50) ACHEALDH1A1LMNACYP3A4HSD17B10
SCHEMBL31590424 0.85 ACHE (0.50) ACHEALDH1A1LMNACYP3A4HSD17B10
SCHEMBL31590529 0.83 ACHE (0.44) ESR2ACHEALDH1A1CYP3A4
SCHEMBL9325323 0.83 CYP3A4 (0.48) CA12ALDH1A1CA2CYP3A4CA9
SCHEMBL21579150 0.81 NR1I2 (0.30) NR1I2
SCHEMBL15985382 0.79 TSHR (0.41) NR1I2ALDH1A1
SCHEMBL28912 0.79 ESR1 (0.50) ESR1ESR2ACHENR1I2NR1H2
SCHEMBL20590779 0.78 UNG (0.46) CA12ALDH1A1CA2CA9
SCHEMBL15985232 0.78 ACHE (0.47) ACHEALDH1A1LMNAHSD17B10
SCHEMBL14740775 0.78 CA12 (0.50) ACHECA12ALDH1A1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986586-A Vinyl-terminated silicone rubber raw rubber and preparation method and application thereof 郑州轻工业大学 2024-05-07 CN claimed
US-10563017-B2 Temperature-resistant silicone resins THE BOEING COMPANY (US) 2020-02-18 US claimed
US-20180072887-A1 TEMPERATURE-RESISTANT SILICONE RESINS THE BOEING COMPANY 2018-03-15 US claimed
US-20160185919-A1 TEMPERATURE-RESISTANT SILICONE RESINS THE BOEING COMPANY 2016-06-30 US claimed
WO-2025245137-A1 POLYMERIC COMPOSITIONS AND PRODUCTS OF LOW WEAR AND OF LOW FRICTION W. L. GORE & ASSOCIATES, INC. (US) 2025-11-27 WO disclosed
US-20250353970-A1 POLYMERIC COMPOSITIONS AND PRODUCTS OF LOW WEAR AND OF LOW FRICTION W. L. GORE & ASSOCIATES, INC. 2025-11-20 US disclosed
US-20250066573-A1 ARTICLES CONTAINING EXPANDED POLY (TETRAMETHYL-p-SILPHENYLENESILOXANE) AND METHODS FOR PRODUCING THE SAME W. L. GORE & ASSOCIATES, INC. 2025-02-27 US disclosed
US-12163003-B2 Articles containing expanded poly (tetramethyl-p-silphenylenesiloxane) and methods for producing the same W. L. GORE & ASSOCIATES, INC. (US) 2024-12-10 US disclosed
US-20240376282-A2 ARTICLES CONTAINING EXPANDED POLY (TETRAMETHYL-p-SILPHENYLENESILOXANE) AND METHODS FOR PRODUCING THE SAME W. L. GORE & ASSOCIATES, INC. 2024-11-14 US disclosed
EP-3269756-B1 TEMPERATURE-RESISTANT SILICONE RESINS BOEING CO (US) 2024-09-11 EP disclosed
CN-117986586-A Vinyl-terminated silicone rubber raw rubber and preparation method and application thereof 郑州轻工业大学 2024-05-07 CN disclosed
CN-115768823-B Articles containing expanded poly (tetramethyl-p-silphinylideneamide) and methods of making the same W.L.戈尔及同仁股份有限公司 2024-02-13 CN disclosed
US-20170101510-A1 TEMPERATURE-RESISTANT SILICONE RESINS THE BOEING COMPANY 2017-04-13 US disclosed
US-9534089-B2 Temperature-resistant silicone resins THE BOEING COMPANY (US) 2017-01-03 US disclosed
US-20160185919-A1 TEMPERATURE-RESISTANT SILICONE RESINS THE BOEING COMPANY 2016-06-30 US disclosed
US-9309359-B2 Temperature-resistant silicone resins THE BOEING COMPANY (US) 2016-04-12 US disclosed
US-20160009864-A1 TEMPERATURE-RESISTANT SILICONE RESINS THE BOEING COMPANY 2016-01-14 US disclosed
US-20160009867-A1 TEMPERATURE-RESISTANT SILICONE RESINS THE BOEING COMPANY 2016-01-14 US disclosed
EP-2966115-A2 TEMPERATURE-RESISTANT SILICONE RESINS The Boeing Company (US) 2016-01-13 EP disclosed
EP-2966114-A1 TEMPERATURE-RESISTANT SILICONE RESINS The Boeing Company (US) 2016-01-13 EP disclosed