SCHEMBL28912

SCHEMBL28912

C[Si](C)(O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
NR1I2 O75469 9/20 0.48
NR1H2 P55055 2/20 0.43
NR1H3 Q13133 2/20 0.43
RORA P35398 1/20 0.41
RORC P51449 1/20 0.41
RORB Q92753 1/20 0.41
NR1H4 Q96RI1 1/20 0.41
MAPT P10636 1/20 0.39
CA4 P22748 2/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
TSHR P16473 2/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
GLA P06280 1/20 0.35
CA3 P07451 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28018450 0.97 ESR1 (0.48) ESR1ESR2NR1I2NR1H2NR1H3
Potassium SCHEMBL31414604 0.97 ESR1 (0.48) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL29217062 0.97 ESR1 (0.48) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL2143983 0.97 ESR1 (0.48) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL31081430 0.97 NR1I2 (0.52) ESR1ESR2NR1I2NR1H2NR1H3
Magnesium Chloride Anhydrous SCHEMBL28382622 0.89 NR1I2 (0.43) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL235602 0.83 NR1I2 (0.43) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL273322 0.81 NR1H2 (0.59) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL271787 0.81 ESR1 (0.50) ESR1ESR2NR1I2NR1H2NR1H3
SCHEMBL439492 0.80 ESR1 (0.48) ESR1ESR2NR1I2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1943 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120037974-A Preparation method and application of nickel homogeneous hydrogenation catalyst 中国石油天然气股份有限公司 2025-05-27 CN claimed
CN-119529476-A Epoxy resin composition, preparation method and epoxy glass cloth laminated board 深圳市雄毅华绝缘材料有限公司 2025-02-28 CN claimed
CN-119431708-A In-situ inorganic hybridization reinforced polyurethane resin and preparation method thereof 丰源和泰(兰州)新材料有限公司 2025-02-14 CN claimed
CN-118813056-B High-foaming-rate liquid silicone rubber foam material and preparation method and application thereof 浙江申禾丽阳科技有限公司 2025-01-24 CN claimed
CN-118813056-A High-foaming-rate liquid silicone rubber foam material and preparation method and application thereof 浙江申禾丽阳科技有限公司 2024-10-22 CN claimed
CN-117924680-B Degradable polyester knitted fabric and preparation process thereof 江苏贝尔特福新材料股份有限公司 2024-06-21 CN claimed
CN-116656211-B Water-based epoxy insulating paint and preparation method thereof 国网安徽省电力有限公司超高压分公司 2024-06-04 CN claimed
CN-117986586-A Vinyl-terminated silicone rubber raw rubber and preparation method and application thereof 郑州轻工业大学 2024-05-07 CN claimed
CN-117924680-A Degradable polyester knitted fabric and preparation process thereof 江苏贝尔特福新材料股份有限公司 2024-04-26 CN claimed
CN-117801316-A Composite polyether silicone oil emulsifier and preparation method and application thereof 万华化学集团股份有限公司 2024-04-02 CN claimed
EP-0415070-A2 Flame retardant aromatic polycarbonate compositions GENERAL ELECTRIC COMPANY (US) 1991-03-06 EP claimed
CN-88102982-A Polyimide resin composition 1988-12-21 CN claimed
EP-0278157-A2 A rubber composition Shin-Etsu Chemical Co., Ltd. (JP) 1988-08-17 EP claimed
US-4714733-A VULCANIZABLE BLEND OF RUBBER, UNSATURATED POLYSILOXANE, SILICA FILLER, AND THIOCARBAMYL-CONTAINING ORGANOSILANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1987-12-22 US claimed
US-4663397-A Thermosetting resin composition TORAY SILICONE CO., LTD. (JP) 1987-05-05 US claimed
EP-0201176-A2 Thermosetting resin composition Toray Silicone Company Limited (JP) 1986-11-12 EP claimed
US-4267117-A INTERMEDIATES FOR 1A-HYDROXYLATED CALCIFEROLS THE UPJOHN COMPANY (US) 1981-05-12 US claimed
US-4206131-A 1A-HYDROXYLATED CALCIFEROLS THE UPJOHN COMPANY (US) 1980-06-03 US claimed
US-4039666-A ANTICONVULSANT PHENYLSILANES DOW CORNING CORPORATION (US) 1977-08-02 US claimed
US-3993839-A ORGANO-SILOXY TITANIC ACID ESTERS SHINETSU CHEMICAL COMPANY (JA) 1976-11-23 US claimed