SCHEMBL17415087

SCHEMBL17415087

Cc1cccc(-c2cccc3c2C=CC3[Hf](C)(C)(C2C=Cc3c(-c4cccc(C)c4)cccc32)=[Si](C)CCc2ccccc2)c1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
GRIN2B Q13224 1/20 0.32
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
ALOX12 P18054 1/20 0.31
CES2 O00748 1/20 0.31
HTR7 P34969 1/20 0.30
KMT2A Q03164 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17415526 0.93
SCHEMBL17416055 0.91
SCHEMBL17415675 0.90 FFAR1 (0.30) FFAR1FFAR4
SCHEMBL17415846 0.87
SCHEMBL17415392 0.87 RXRA (0.31)
SCHEMBL17415557 0.87 RXRA (0.31)
SCHEMBL17415645 0.87 MEN1 (0.30) KMT2A
SCHEMBL17415022 0.85
SCHEMBL17415782 0.85 HTR7 (0.30) HTR7
SCHEMBL17415090 0.85 MAOB (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2966096-B1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP (JP) 2017-04-26 EP disclosed
EP-2966096-A1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER Japan Polyethylene Corporation (JP) 2016-01-13 EP disclosed